Christopher R. G. Jones;Alain D. Baron;Mark S. Fineman;Martin R. Brown
发明人:
Alain D. Baron,Martin R. Brown,Christopher R. G. Jones,Mark S. Fineman
申请号：
US13276177
公开号：
US09486463B2
申请日:
2011.10.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein are methods of modulating hormone concentrations in a subject comprising the administration of a composition comprising a chemosensory receptor ligand, wherein the composition is adapted to deliver the ligand to one or more regions of the intestine of said subject. Also provided are methods directed to the modulation of circulating concentrations of one or more of GLP-1 (total), GLP-1 (active), GLP-2, oxyntomodulin, PYY (total), PYY 3-36, CCK, GIP, insulin, C-peptide, glycentin, uroguanylin amylin, and ghrelin (total), ghrelin (active) and glucagon.
