Patrick BAEUERLE,Luke EVNIN,Jeanmarie GUENOT,Holger WESCHE
申请号：
US16339263
公开号：
US20190225702A1
申请日:
2017.10.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein are trispecific antigen-binding proteins comprising a domain binding to innate immune cells, a half-life extension domain, and a domain binding to a target antigen. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such trispecific antigen-binding proteins. Also disclosed are methods of using the disclosed trispecific antigen-binding proteins in the prevention, and/or treatment diseases, conditions and disorders.
