ALESSANDRO SETTE,ROBERT CHESNUT,BRIAN D. LIVINGSTON,DENISE MARIE BAKER,MARK J. NEWMAN
申请号:
BR0017052
公开号:
BR0017052B1
申请日:
2000.12.28
申请国别(地区):
BR
年份:
2013
代理人:
摘要:
This present invention relates to the field of biology. In particular, it relates to polyepitopic vaccines and methods of designing such vaccines to provide increased immunogenicity. In certain embodiments, the polyepitopic vaccines is encoded by a minigene that provides optimized immunogenicity of the construct.