Refer to methods for immunomodulation with Antibodies that specifically bind to the Antigen CD38, characterized in that it comprises the hcdr1, hcdr2, hcdr3, lcdr1,The lcdr2 and lcdr3: (a) The VH of the sec. With no. ident: 14 and the VL of the sec. With no. ident: 15 (b) The VH of the sec. With no. 16 and ident: The VL of the sec. With no. Ident.: 17 (c) The VH of the sec. With no. ident: 18 and the VL of the sec. With no. ident: 19 (d) The VH of the sec. With no. ident: 20 and the VL of the sec. With no. ident: 21.It also refers to the Administration of therapeutically effective amount of the Antibody and Treatment of patients with Solid tumors.Referido a metodos para la inmunomodulacion con anticuerpos que se unen especificamente a CD38, caracterizado porque el anticuerpo comprende la HCDR1, la HCDR2, la HCDR3, la LCDR1, la LCDR2 y la LCDR3 de: a) la VH de la sec. con num. de ident.: 14 y la VL de la sec. con num. de ident.: 15 b) la VH de la sec. con num. de ident.: 16 y la VL de la sec. con num. de ident.: 17 c) la VH de la sec. con num. de ident.: 18 y la VL de la sec. con num. de ident.: 19 d) la VH de la sec. con num. de ident.: 20 y la VL de la sec. con num. de ident.: 21. Tambien se refiere a la administracion de la cantidad terapeuticamente eficaz del anticuerpo y tratamiento de pacientes que tienen tumores solidos.
