Compositions and methods of inhibiting masp-1, masp-2 and/or masp-3 for treatment of paroxysmal nocturnal hemoglobinuria

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专利权人:

UNIVERSITY OF LEICESTER;OMEROS CORPORATION

发明人:

Demopulos Gregory A.,Schwaeble Hans-Wilhelm

申请号：

NZ62967513

公开号：

NZ629675A

申请日:

2013.04.05

申请国别(地区):

NZ

年份:

2017

代理人:

摘要：

Disclosed is the use of a MASP-3 inhibitory agent in the manufacture of a medicament for treating a subject suffering from paroxysmal nocturnal hemoglobinuria (PNH), wherein said MASP-3 inhibitory agent is a MASP-3 monoclonal antibody, or fragment thereof that specifically binds to a portion of SEQ ID NO:8 and inhibits factor D maturation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/