COMPOSITIONS ET PROCÉDÉS POUR AMÉLIORER LE BÉNÉFICE THÉRAPEUTIQUE DE COMPOSÉS CHIMIQUES ADMINISTRÉS DE MANIÈRE SUBOPTIMALE, NOTAMMENT DES HEXITOLS SUBSTITUÉS TELS QUE LE DIBROMODULCITOL
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to substituted hexitols such as dibromodulcitol or analogs, derivatives, or prodrugs thereof.