Removal of high molecular weight aggregates using hydroxyapatite chromatography

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专利权人:

ワイス・エルエルシー

发明人:

シュジュン・スン,クリストファー・ガロ,ブライアン・ケリー

申请号：

JP2012013648

公开号：

JP5490156B2

申请日:

2012.01.26

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

This invention relates to the application of hydroxyapatite chromatography to the purification of at least one antibody from a preparation containing high molecular weight aggregates. Further, this invention relates to an integration of ceramic hydroxyapatite chromatography into a combination chromatographic protocol for the removal of high molecular weight aggregates from an antibody preparation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/