A method, medical imaging workstation (300) and a hybrid medical imaging scanner (400) are provided for the analysis of images obtained during medical scans. The extent of a first region of interest (ROI-1) in a first scan image (120) is defined. A second region (ROI-2), in a second scan image (130), is identified. The second region (ROI-2) in the second scan image (130) corresponds to the first region of interest (ROI-1) in the first scan image. Each of the spatial locations of the second region (ROI-2) is classified, in order to identify the spatial locations of the second region (ROI-2) that comprise at least one tissue type. The invention may improve the recognition of lesions in medical scan images, and may reduce the incidence of false positives.
