The invention refers to a medication delivery device (1) comprising a housing (3) having a proximal and a distal end, a medication receptacle (2) designed to be engaged with the distal end of the housing (3) by engagement of first engagement means (5) with second engagement means (4) and a dosing mechanism. The dosing mechanism includes a piston rod (17) which is moveable in a distal direction for medication delivery and a drive device for moving the piston rod (17) in the distal direction for medication delivery. The medication receptacle (2) comprises an actuation means (70) for bringing and holding a guiding means (11) in a guiding position in which the guiding means (11) guides the piston rod (17) for medication delivery. The first engagement means (5) and the second engagement means (4) are moveable into engagement by a movement of the medication receptacle (2) which ends in a rotational movement without axial movement of the medication receptacle (2) with respect to the housing (3), the actuation means (70) thereby bringing the guiding means (11) in the guiding position.本發明關於一種給藥裝置(1)，其包括一具有一近端和一遠端的殼體(3)，一經設計欲藉由第一接合構件(5)與第二接合構件(4)之接合而與該殼體(3)之遠端接合的藥物容器(2)，及一投藥機構。該投藥機構包含一可依一遠端方向移動以進行給藥的活塞桿(17)及一用於使該活塞桿(17)依遠端方向移動以進行給藥的驅動裝置。該藥物容器(2)包括一用於將一引導構件(11)帶入並保持在一引導位置的致動構件(70)，在該引導位置中該引導構件(11)導引該活塞桿(17)以進行給藥。該第一接合構件(5)和該第二接合構件(4)可因該藥物容器(2)之一運動而被移至接合狀態，該運動係終止於該藥物容器(2)相對於該殼體(3)之一無軸向運動的旋轉運動，該致動構件(70)藉此將該引導構件(11)帶入該引導位置。
