The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.本發明係關於新穎經取代吲唑、關於其製法、關於其單獨或組合用於治療及/或預防疾病之用途,且關於其用於製備用以治療及/或預防疾病、尤其用以治療及/或預防以下疾病之藥劑之用途:子宮內膜異位症及子宮內膜異位症相關性疼痛及其他子宮內膜異位症相關性症狀(例如痛經、性交疼痛、排尿困難及排糞困難)、淋巴瘤、類風濕性關節炎、脊椎關節炎(尤其牛皮癬性脊椎關節炎及別赫捷列夫氏病(Bekhterev's disease))、紅斑性狼瘡、多發性硬化、黃斑部病變、COPD、痛風、脂肪肝病症、胰島素抗性、贅瘤性病症及牛皮癬。