Topical pharmaceutical compositions are described comprising, based on the total weight of the composition:(a) 4.0-5.5 wt.% of diclofenac sodium；(b) 1.5-3.0 wt.% of hyaluronic acid, a salt thereof or mixtures thereof；(c) 50-60 wt.% of water； and(d) 30-40 wt.% of a carrier or vehicle other than water.Said compositions are stable and can be safely and easily applied over large surface areas of the skin in an acceptable way by the general patient population for the treatment or prevention of some skin disorders or diseases.
