A COMBINED VACCINE, COMPRISING A PRIMER COMPOSITION COMPRISING A MENINGOCOCCAL OUTER MEMBRANE VESICLE PREPARATION, AND A BOOSTER COMPOSITION COMPRISING A MENINGOCOCCAL PROTEIN ANTIGEN PREPARATION
Disclosed is the use of a primer composition comprising a meningococcal outer membrane vesicle preparation, and a booster composition comprising a purified meningococcal protein antigen preparation, wherein the booster composition does not comprise outer membrane vesicles, for the preparation of a pharmaceutical combination for immunizing a subject against a disease caused by Neisseria meningitidis