Harisha Atluri,Ching Wah Chong,Robert Kuehl,Cassandra Shu,Pearl Shwe-Cho Tay,James Francis Hulvat,Alexander Jacob McVey,Ryan Mitchell Minikis
申请号:
US15462444
公开号:
US10105368B2
申请日:
2017.03.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein is the Brutons tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.