ANTIBODIES THAT BIND LGR4

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专利权人:

发明人:

申请号：

EP15811302.7

公开号：

EP3157634A4

申请日:

2015.06.17

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Disclosed herein are anti-LGR4 antibodies for the treatment of cancer. Antibodies disclosed herein may bind LGR4 without disrupting LGR4-RSPO1 binding or signaling, and may disrupt LGR4 signaling through Wnt that is independent of RSPO1. Also disclosed are heavy and light chain polypeptide sequences for antibodies that bind LGR4, for example without disrupting LGR4-RSPO binding or signaling.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/