Hsing-Wen Sung,Ha Giang Thi Nguyen,Fang Yi Su,Li-Wen Hsu,Er-Yuan Chung,Hosheng Tu
申请号：
US13776111
公开号：
US08535640B1
申请日:
2013.02.25
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
