John D. Cleary,Stanley W. Chapman,Robert E. Kramer
申请号:
US12985256
公开号:
US08648050B2
申请日:
2011.01.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method of ameliorating amphotericin treatment side effects in a mammal that comprises administering a therapeutically effective amount of a formulation that comprises a polyene active ingredient that includes amphotericin B, wherein the amphotericin B compound is present, in terms of polyene content, in an amount greater than 90%, and non-amphotericin B polyene compounds are present in an amount of no greater than 10%, and a pharmaceutically effective carrier and administering a therapeutically effective amount of said formulation to a subject in need thereof.