HMGN2 PEPTIDES AND RELATED MOLECULES THAT SELECTIVELY HOME TO TUMOR BLOOD VESSELS AND TUMOR CELLS

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专利权人:

Erkki Ruoslahti

发明人:

Erkki Ruoslahti,Kimmo Porkka,Sven Christian

申请号：

US13276237

公开号：

US20120121501A1

申请日:

2011.10.18

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/