PROBLEM TO BE SOLVED: To provide a new marker capable of evaluating the progress or degree of a cerebrovascular disorder and a cardiovascular disorder, to provide a screening method of a preventive therapeutic agent of a cerebrovascular disorder and a cardiovascular disorder using the marker, and to provide a preventive therapeutic agent of a cerebrovascular disorder and a cardiovascular disorder.SOLUTION: In the screening method of a preventive therapeutic agent of a cerebrovascular disorder or a cardiovascular disorder, reinforcement operation of a substance to be inspected to the manifestation of a liver-type fatty acid-binding protein in an animal cell is examined.COPYRIGHT: (C)2010,JPO&INPIT【課題】脳血管障害及び心血管障害の進展や程度を評価することができる新たなマーカー、当該マーカーを用いた脳血管障害及び心血管障害の予防治療薬のスクリーニング方法、並びに脳血管障害及び心血管障害の予防治療薬を提供する。【解決手段】動物細胞における肝臓型脂肪酸結合蛋白の発現に対する被験物質の増強作用を検定することを特徴とする脳血管障害又は心血管障害の予防治療薬のスクリーニング方法。【選択図】なし
