UTILISATION CONJOINTE DUN INHIBITEUR DE TRKA ET DUN INHIBITEUR DE EPHA2 POUR UNE UTILISATION DANS LE TRAITEMENT DE CANCERS SOLIDES ET MÉTHODE DE PRONOSTIC DE LA SURVIE DE PATIENT SOUFFRANT DUN CANCER SOLIDE

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专利权人:

UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE

发明人:

TOILLON, Robert,LE BOURHIS, Xuefen,CORBET, Cyril,AUBERT, Léo,GUILBERT, Matthieu

申请号：

EP15771188.8

公开号：

EP3193938A1

申请日:

2015.09.07

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention relates to an EphA2 inhibitor for the use thereof in the treatment of solid cancer treated with a TrkA inhibitor, and a TrkA inhibitor for the use thereof in the treatment of solid cancer treated with an EpbA2 inhibitor. The invention also relates to a method for the prognosis of survival of a patient who has a solid cancer, comprising a step of detecting the expression of TrkA and EphA2 in a biological sample of the patient, the co-expression of TrkA and EphA2 being associated with a poor prognosis of survival of the patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/