Dennis Jul Hansen,Christoph Rosenbohm,Michael Meldgaard
申请号：
US15771206
公开号：
US10577388B2
申请日:
2016.09.29
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to the field of oligonucleotide conjugates and to methods of synthesis thereof. In the present method a low-water content solvent environment allows a more efficient conjugation, reducing the amount of conjugate moiety needed and increasing the conjugation reaction speed.
