Items related to the following items: cosmetic fluid, milk liquid, lotion, cream, gel, essence, lip cream, pack, hair tonic, hair cream, hair cosmetics such as hair cream, hair cosmetics, medicinal cosmetics and scalp agents for external use of skin such as cosmetics or scalp agents In this case, a culture medium obtained by fermentation with nicotinamide mononucleotide and yeast bacteria which is excellent in moisturizing effect and skin roughness improvement effect which can be used for the skin external use containing the base material, and having a little sense of stimulation is provided.The present invention relates to a skin external charge characterized by containing a mixture of nicotinamide mononucleotide and a culture medium fermented by yeast.No selection【課題】化粧水、乳液、ローション、クリーム、ジェル、エッセンス、リップクリーム、パック、ヘアトニック、ヘアクリームなどの化粧品や薬用化粧品及び頭皮用剤などの皮膚の外用に供する医薬部外品又は皮膚外用薬の基剤を含む皮膚外用料に利用することができる保湿効果や肌荒れ改善効果に優れ、しかも刺激感も少ないニコチンアミドモノヌクレオチド及び酵母菌で発酵した培養液を提供する。【解決手段】保湿効果や肌荒れ改善効果に優れ、しかも刺激性もすくないニコチンアミドモノヌクレオチドと酵母菌で発酵した培養液を含有することを特徴とする皮膚外用料に関する。【選択図】なし