Jean-Paul Castaigne,Michel Demeule,Catherine Gagnon,Betty Lawrence
申请号：
US13124013
公开号：
US08921314B2
申请日:
2009.10.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a GLP-1 agonist (e.g., exendin-4 or an exendin-4 analog). The compounds of the invention can be used to treat any disease where increased GLP-1 activity is desired, for example, metabolic diseases, such as obesity and diabetes.
