Use of a linear DNA expression construct with covalently closed ends

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专利权人:

发明人:

申请号：

EP10195929.4

公开号：

EP2428228A1

申请日:

2010.12.20

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates to a linear DNA expression construct having covalently closed ends, comprising an expression cassette comprising a coding sequence encoding for a gene therapy anti-cancer agent for use in the treatment of cancer, wherein said DNA expression construct is suitable for administration into cells or tissues by a physical transfection method. Preferably, said DNA expression construct consists of a dumbbell-shaped circular strand of DNA.

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