ALAM, JENEFER,HO, SOO YEI,WANG, WEI LING,DURAISWAMY, ATHISAYAMANI JEYARAJ
申请号：
CA2933683
公开号：
CA2933683A1
申请日:
2014.12.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to dihydropyrazolo[l,5-a]pyrimidine compounds of formula I, defined herein, as WNT pathways modulators, processes for making them, and pharmaceutical compositions comprising them. Methods of treatment of conditions mediated by WNT pathway signalling including cancer, fibrosis, stem cell and diabetic retinopathy, rheumatoid arthritis, psoriasis and myocardial infarction, comprising the compounds of formula I are also provided.
