Imclone LLC;Philadelphia Health & Education Corporation D/b/a Drexel University, College of Medicine;The University of Washington
发明人:
申请号:
EP12162951.3
公开号:
EP2505205A1
申请日:
2006.06.19
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention concerns an isolated human antibody or antibody fragment specific for PDGFRα comprising one or more complementarity determining regions selected from a group specified in the specification. The invention also relates to polynucleotides encoding the antibody or fragment thereof, expression vectors comprising such polynucleotides and recombinant host cells comprising the vectors.The antibodies may be used for inhibiting tumor growth in a mammal.