596498 An integrated iontophoretic transdermal patch adapted for the delivery of therapeutic anti-migraine agents to a subject in need thereof, the iontophoretic transdermal patch comprising:(a) an iontophoretic transdermal patch containing an amount of an active anti-migraine agent in the form of a triptan compound or a salt thereof integrated with (b) electronic components configured to provide two-stage patterned delivery sequence which includes an initial first stage delivery at a relatively high rate followed by a second stage delivery at a lower rate, said patch being further characterized by a power/area ratio wherein the average current density is less than 250 ?A/cm2.
