PETERFREUND ROBERT A,PARKER MICHAEL J,SIMS NATHANIEL M,LOVICH MARK A,DEMONACO HAROLD J
申请号:
IN4366/DELNP/2014
公开号:
IN2014DN04366A
申请日:
2014.05.29
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
Systems for predicting a drug delivery profile as described herein include at least one drug pump and/or a controllable valve that produce a drug flow. The drug pump and/or controllable valve dispense at least a first drug. The system also includes at least one carrier fluid pump and/or another controllable valve that produces a carrier fluid flow a flow junction structure configured to receive the drug flow and the carrier fluid flow to produce a mixed flow and a fluid path for carrying the mixed flow between the flow junction structure and a delivery point. The system further includes a processing device configured to predict the drug delivery profile at the delivery point based on determining a predicted time variation of drug concentration at the delivery point using at least a model of the mixed flow. The model includes a plurality of parameters related to propagation of the mixed flow through the fluid path.