COVALENT LINKERS IN ANTIBODY DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME

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专利权人:

发明人:

HUANG CHANG JIANG,FANG JIANMIN,YE HUI,ZHANG LEZHI

申请号：

IN201827009117

公开号：

IN201827009117A

申请日:

2018.03.13

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention provides novel and advantageous compositions having a linker capable of covalently coupling one or more free thiols of an antibody. Specifically provided herein are the molecular structures synthetic pathways coupling mechanisms and applications thereof as used in an antibody drug conjugate (ADC).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/