Wenhui Zhou,Hui Wang,James J. Cali,Sarah Duellman,Jolanta Vidugiriene,Natasha Karassina
申请号：
US16523384
公开号：
US20200030456A1
申请日:
2019.07.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Conjugates comprise a drug or probe, a cell binding agent, and a quinone-containing linker. The quinone-containing linker may be reduced intracellularly to trigger release of the drug or probe. These conjugates may selectively deliver a drug or probe to a site of action of interest for local release of the active drug or probe.
