UNDERWOOD DENNIS J,LEGER OLIVIER,SIEBERT VOLKER,VAN DIJK MARC,SCHAER DAVID,TSUJL TAKEMASA,RITTER GERD,GONZALEZ ANA M,WILSON NICOLAS S,ZAPPASODI ROBERTA,MERGHOUB TAHA,WOLCHOK JEDD DAVID
申请号：
IN201617044595
公开号：
IN201617044595A
申请日:
2016.12.28
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human GITR and modulate GITR activity, e.g., enhance, activate or induce GITR activity, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as cancer and infectious diseases, by administering an antibody that specifically binds to human GITR and modulates GITR activity e.g., enhances, activates or induces GITR activity.
