It refers to a kind of efficacy synthesis in aerosol solution, which is used for pressure dose inhaler, including: (a) brominated glycerin with 5-26 mg dose； (b) formaldehyde, salt or the solution of such salt, with the dose between 1-25 UG； (c) A propellant consisting of hydrofluorocarbons； (d) a sewing agent； and (E) an effective amount of stable mineral acid. This component is contained in an aerosol tank lined with a fluoroethylene propylene (FEP) resin. In one preferred aspect, the mineral anhydrides are hydrochloric acid 1m,The stabilizer content is between 0.15 and 0.28 μ g / L, while the cosmetics are ethanol. On the other hand, this component may include one or more active pharmaceutical components, selected from β - 2 agonists； corticosteroids used for inhalation (dibutyric acid of beclomethasone, Ferdinand, propionic acid of fluticasone, trimethylquinolone, prednisone, etc.)；Corrosion inhibitors and phosphoric acid-4 inhibitors. Store this ingredient in an internally packaged aluminum can, as previously described, to minimize degradation products (especially DP3) during its shelf life, even when stored in severe cold and humidity conditions below the detection threshold.Se refiere a una composicion farmaceutica en solucion para aerosol para utilizar en un inhalador presurizado de dosis medida que comprende: a) bromuro de glicopirronio con una dosificacion entre 5 y 26 ug por accionamiento； b) formoterol, o una sal del mismo o un solvato de dicha sal, con una dosificacion entre 1 y 25 ug por accionamiento； c) un propelente que consiste en un HFA； d) un cosolvente； y e) un acido mineral como estabilizante en una cantidad util. Dicha composicion esta contenida en una lata de aerosol recubierta internamente por una resina que comprende un copolimero de etileno–propileno fluorado (FEP). En un aspecto preferido, el acido mineral es acido clorhidrico 1M, en una cantidad entre 0,15 y 0,28 ug/ul como estabilizante； y el cosolvente es etanol. En otro aspecto, dicha
