#$%^&*AU2018102138A620190919.pdf#####ABSTRACT A device for diagnosing a brain injury in a subject, comprising: a probe, said probe comprises a porous matrix； and an indicator formulation disposed in and/or on said porous matrix and comprises at least one glycan-based biomarker binding reagent for selectively binding to a glycan-based biomarker in a sample, and a first visually detectable label； wherein: at least one of said glycan-based biomarker binding reagent and/or said first visually detectable label is immobilized in and/or on a detection zone in said porous matrix； said glycan-based biomarker is indicative of brain injury； said first visually detectable label develops a color and becomes visible upon a binding event of said glycan-based biomarker to said glycan-based biomarker binding reagent； and said binding event is effected by contacting said sample with said probe.
