HYDROXYMETHYLARYL-SUBSTITUTED PYRROLOTRIAZINES AND USES THEREOF农业专利-农业学术服务平台

发明人:: KLAR, JUERGEN,卡尔尤尔根,卡爾尤爾根,VOEHRINGER, VERENA,佛林格韦雷娜,佛林格韋雷娜,TELSER, JOACHIM,特尔沙约阿希姆,特爾沙約阿希姆,LOBELL, MARIO,罗贝尔马里奥,羅貝爾馬里奧,SUESSMEIER, FRANK,苏斯梅尔法兰克,蘇斯梅爾法蘭克,LI, VOLKHART MIN-JIAN,李民坚,李民堅,BOETT

摘要：: This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.本發明係關於新穎的經5-[(羥甲基)芳基]-取代之吡咯并[2,1-f][1,2,4]三-4-胺、製備此等化合物之方法、包含此等化合物之醫藥組成物以及此等化合物或組成物於治療血管新生相關病症,特別是血管新生有關的眼睛病症之用途。