A system for treating an annular defect of an intervertebral disc is provided. The system comprises a cannula for accessing a nucleus pulposus of the intervertebral disc, an expandable spacing device, and a material delivery instrument. The expandable spacing device has a first deflated position and a second inflated position. The spacing device is sized to pass through the cannula when in the first deflated position and the spacing device has a predetermined shape in the second inflated position. The material delivery instrument is adapted to inflate the spacing device from the first deflated position to the second inflated position by injecting a biocompatible material into the spacing device. In another aspect, a method of treating at least one annular defect of an intervertebral disc is provided.