COMBINATION USE OF INHIBITOR TARGETING PD-1/PD-L1 AND COX-2 INHIBITOR

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专利权人:

NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY;FUSO PHARMACEUTICAL INDUSTRIES, LTD.

发明人:

Satoru KONNAI,Kazuhiko OHASHI,Shiro MURATA,Tomohiro OKAGAWA,Naoya MAEKAWA,Asami NISHIMORI,Shinya GOTO,Yasuhiko SUZUKI,Chie NAKAJIMA,Yamato SAJIKI

申请号：

US16630908

公开号：

US20200131270A1

申请日:

2018.07.19

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention provides a novel therapeutic strategy using an inhibitor targeting PD-1/PD-L1. A pharmaceutical composition which comprises a COX-2 inhibitor and is administered before, after or simultaneously with the administration of an inhibitor targeting PD-1/PD-L1. A potentiator for the immunostimulatory effect of an inhibitor targeting PD-1/PD-L1, which comprises a COX-2 inhibitor.

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http://www.ckcest.cn/home/