This invention generally providescompounds, pharmaceutical compositions,and methods for their use, which includemethods that result in increased expression inan Atoh1 gene (e.g., Hath1) in a biological cell.More specifically, the invention relates to thetreatment of diseases and/or disorders thatwould benefit from increased Atoh1 expression,e.g., a hearing impairment or imbalancedisorder associated with a loss of auditory haircells, or a disorder associated with abnormalcellular proliferation.
