Gabriel Ghiaur,Richard J. Jones,Alonso Salvador,Roshantha A. Chandraratna
申请号:
US15777868
公开号:
US20180333380A1
申请日:
2016.11.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are methods for treating a cancer comprising administering to a subject in need thereof an effective dose of a CYP26-resistant retinoic acid receptor (RAR) alpha (RARα) selective agonist, whereby as a result of the treatment the tumor burden is reduced in the subject and cancer stem cells resident in the bone marrow are substantially reduced.