Pharmaceutical composition the present invention relates to new substituted thiocarbamoyl imidazole alkanone compound and comprising the compound, it treats androgen-receptor related diseases or illness, such as prostate cancer, benign prostatic hyperplasis, male alopecia, muscle loss, acne and hirsutism with what.本發明涉及新的取代的硫代咪唑烷酮化合物以及包含所述化合物的藥物組合物,其用於治療雄激素受體相關疾病或病症,例如前列腺癌、良性前列腺增生、雄性脫髮、肌肉損失、痤瘡和多毛症。