FERNANDES GOMES DOS SANTOS, PAULO ANTONIO,HOGENAUER, KLEMENS,HOLLINGWORTH, GREGORY,SOLDERMANN, NICOLAS,STOWASSER, FRANK,TUFILLI, NICOLA,ZECRI, FREDERIC
申请号：
CA2840315
公开号：
CA2840315A1
申请日:
2012.06.25
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The invention relates to crystalline anhydrous forms, crystalline solvate forms and/or salt forms including crystalline salt forms of {(S)-3-[6-(6-methoxy-5-methyl-pyridin-3-yl)-5,6,7,8- tetrahydro-pyrido[4,3-d]pyrimidin-4-yloxy]-pyrrolidin-1-yl}-(tetrahydro-pyran-4-yl)-methanone or salt forms including crystalline salt forms of 1-{(S)-3-[6-(6-methoxy-5-trifluoromethyl- pyridin-3-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ylamino]-pyrrolidin-1-yl}-propan-1-on； pharmaceutical compositions and combinations including these forms as well as to methods of using these forms, including their pharmaceutical compositions and combinations for the treatment of diseases.
