Timmermand, Pär Oskar Vilhelmsson,Tran, Amanda Thuy,Strand, Sven-Erik,Lamminmäki, Urpo Juhani,Sjöström, Kjell
申请号：
HRP20191095
公开号：
HRP20191095T1
申请日:
2019.06.17
申请国别(地区):
HR
年份:
2019
代理人:
摘要：
The present disclosure provides antibody polypeptides with binding specificity for human kallikrein-2 (hK2), wherein the antibody polypeptide comprises (a) a heavy chain variable region comprising the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 and SEQ ID NO:3 and/or (b) a light chain variable region comprising the amino acid sequences of SEQ ID NO:4 and SEQ ID NO:5 and SEQ ID NO:6, and wherein the heavy chain variable region and light chain variable region comprise framework amino acid sequences from one or more human antibodies. The disclosure further provides use of said antibody polypeptides in the diagnosis and treatment of prostate cancer
