LEE, Frances, Eun-Hyung,SANZ, Ignacio,NGUYEN, Doan, C.
申请号：
EP20160808268
公开号：
EP3307070(A1)
申请日:
2016.06.09
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要：
This disclosure relates to growth media and environments for in vitro culturing of cells that produce or are capable of producing antibodies. In certain embodiments, the media comprises IL-6, fibronectin, and typically a saccharide. In certain embodiments, the disclosure contemplates cell culture compositions comprising IL-6 and fibronectin that are derived from proteins secreted from mesenchymal stromal/stem cells (MSCs). In certain embodiments, the disclosure contemplates enclosures comprising culture compositions disclosed herein that are in ambient air or optionally in an environment wherein oxygen is absent or at a low concentration.
