The present invention relates to a method for manufacturing an eco-friendly wipe package using 100% Tencel fabric, comprising: a material preparatory step (S1) of preparing a wet tissue solution to be injected to the Tencel fabric in a spray method by including, on the basis of 99 parts by weight of purified water, a preservative comprising 0.15-0.4 parts by weight of isopentyldiol, 0.25-0.4 parts by weight of propanediol, 0.12-0.25 parts by weight of caprylhydroxamic acid, 0.01-0.08 parts by weight of octyldodeceth-16, 0.15-0.4 parts by weight of 1,2-hexanediol, 0.1-0.2 parts by weight of ethylhexylglycerin, and 0.001-0.01 parts by weight of complex extracts; a wet tissue solution spray step (S2) of wetting the Tencel fabric with the wet tissue solution; a Tencel fabric cutting step (S3); a Tencel tissue accumulation step (S4); a pre-packaging step (S5); a packaging material sealing step (S6); and an opening and closing cap attachment step (S7), to manufacture an eco-friendly wipe package. Therefore, the present invention provides an effect of significantly reducing discharge of household waste which is not biodegradable, thereby reducing wet tissue waste which is discharged in such large quantities that the same is defined as an environmental contaminant. Furthermore, a characteristic of the Tencel fabric reduces a discharged amount of the wet tissue waste. Moreover, the present invention provides a relatively soft texture such that wet tissues can be used on a sensitive skin suffering from an atopic disease or skin ailments without irritating the skin. Not only that, even when the added preservative is composed of a minimum degree of chemical substances, antiseptic and antibiotic performances and stability thereof are improved.본 발명 100% 텐셀 원단을 이용한 친환경 물티슈 패키지 제조 방법은 텐셀 원단에 스프레이 방식으로 분사할 물티슈용액을 상기 정제수 99 중량부를 기준으로 상기 보존제를 이소펜틸디올 0.15~0.4 중량부, 프로판디올 0.25~0.4 중량부, 카프릴하이드록사믹애시드 0.12~0.25 중량부, 옥틸도데세스-16 0.01~0.08 중량부, 1,2-헥산디올 0.15~0.4 중량부, 에칠헥실글리세린 0.1~0.2 중량부, 복합 추출