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Novel gpr 119 agonists
专利权人:
CADILA HEALTHCARE LIMITED
发明人:
PINGALI HARIKISHORE,ZAWARE PANDURANG
申请号:
NZ60870811
公开号:
NZ608708A
申请日:
2011.10.05
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Provided are pyrimidine-dioxothiazolidine/dioxooxazolidine derivative compounds of the general formula (I), wherein the variables are as defined in the specification. Examples of the compounds include (Z)-tert-Butyl 4-((6-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)-5-methylpyrimidin-4-yl)oxy)piperidine-1-carboxylate and (Z)-5-(3-((6-((1-(5-bromopyridin-2-yl)piperidin-4-yl)oxy)pyrimidin-4-yl)oxy)benzylidene)thiazolidine-2,4-dione. The compounds are GPR 119 agonists. The compounds may be useful in the treatment of obesity, diabetes and related metabolic disorders.
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中国工程科技知识中心
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