Chandan Das,Ashley A. Jaeger,Thomas J. Pohida,Michael M. Gottesman,Randall H. Pursley,Philip G. McQueen,Nicole Y. Morgan
申请号:
US14166744
公开号:
US09670447B2
申请日:
2014.01.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure is directed to embodiments of microstructured membranes, methods of fabricating microstructured membranes, bioreactors housing microstructured membranes, and methods of using bioreactors and microstructured membranes. In some embodiments, the present disclosure allows culturing of cellular tissues in an environment which more accurately resembles a native environment. In some more specific embodiments, the present disclosure allows culturing of tumor cells on a membrane having a microfabricated pattern which mimics a native vasculature system.