Icahn School of Medicine at Mount Sinai;Yale University;The United States of America, as represented by the Secretary, Department of Health &； Human Services
发明人:
Dennis S. Charney,Sanjay J. Mathew,Husseini K. Manji,Carlos A. Zarate, JR.,John H. Krystal
申请号：
US16844090
公开号：
US20200253894A1
申请日:
2020.04.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>；2 years).
