The present invention provides a method for treating a cancer in a subject in need thereof, comprising administering a specific MDM2 inhibitor to the subject according to a specific dosage regimen and a pharmaceutical composition for use in treating a cancer according to the dosage regimen. The present invention also provides a method for treating liposarcoma in a subject in need thereof, comprising administering a specific MDM2 inhibitor to the subject and a pharmaceutical composition for use in treating liposarcoma, comprising the MDM2 inhibitor.本發明提供一種在所需之病患中用於治療癌症的方法,其包含根據特定給藥方案(dosage regimen)將特定MDM2抑制劑投予至該病患;及一種根據該給藥方案用於治療癌症之醫藥組成物。本發明亦提供一種在所需之病患中治療脂肪肉瘤之方法,其包含將特定MDM2抑制劑投予至該病患;及一種用於治療脂肪肉瘤之包含MDM2抑制劑之醫藥組成物。