A device for delivering light and/or ultrasound across a skin surface is provided. The device has a layered structure comprising a light source and/or an ultrasonic transducer. In one embodiment, the light source comprises an organic light emitting diode or a plurality of printed light emitting diodes and the ultrasonic transducer comprises a piezoelectric coating. The device is electrically coupled to a controller, which is electrically coupled to one or more sensors in contact with the skin surface. The controller is operable to receive sensor data from the sensor and dynamically control the device in response to the received sensor data. The device may be provided with a therapeutic or cosmetic composition to be applied to the skin surface, wherein the light and ultrasound emitted from the device cause transdermal transport of the composition through the skin surface.