PROTEINES DE LIAISON A L'ADN INDUCTIBLES ET OUTILS DE PERTURBATION DU GENOME ET LEURS APPLICATIONS

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专利权人:

THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;PRESIDENT AND FELLOWS OF HARVARD COLLEGE

发明人:

ZHANG, FENG,BRIGHAM, MARK,CONG, LE,KONERMANN, SILVANA,SANJANA, NEVILLE ESPI

申请号：

CA2879997

公开号：

CA2879997A1

申请日:

2013.07.21

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

The present invention generally relates to methods and compositions used for the spatial and temporal control of gene expression that may use inducible transcriptional effectors. The invention particularly relates to inducible methods of altering or perturbing expression of a genomic locus of interest in a cell wherein the genomic locus may be contacted with a non- naturally occurring or engineered composition comprising a deoxyribonucleic acid (DNA) binding polypeptide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/