Maria Pilar Lopez-Deber;Andreas Muhs;David Hickman
发明人:
David Hickman,Maria Pilar Lopez-Deber,Andreas Muhs
申请号：
US13816461
公开号：
US09289488B2
申请日:
2011.08.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The method and constructs disclosed and claimed herein allow to control peptide conformation by modulation of the peptide lipidation pattern, spacer and liposome composition, or via co-administration with small molecules. Accordingly, this technology can be applied to the rational design of liposomal vaccines and for the generation of safer and more efficacious therapies for a range of human disease, in particular those based on misfolded proteins.
