UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人:
KIM, JUNG AHN,김정안,CHO, YOUNG JUN,조영준,NAM, JOO HYUN,남주현,KIM, YU JIN,김유진
申请号：
KR1020110143297
公开号：
KR1020130075093A
申请日:
2011.12.27
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A polyethylene oxide-based block copolymer is provided to be easily purified, to be used as a polymeric material for delivering drugs, and to offer pH and glucose response.CONSTITUTION: A polyethylene oxide-based block copolymer is denoted by chemical formula 1, 2, or 3. In the chemical formulas: R is an n- butyl group, a sec-butyl group, a tert-butyl group, or a tert butoxy group R1 and R2 are hydrogen or a methyl group, respectively m is a fixed number selected from 5-50 n is a fixed number selected from 10-500 and k is a fixed number selected from 1-5. An iron oxide nanoparticle is stabilized by the polyethylene oxide-based block copolymer. A producing method of the iron oxide nanoparticle comprises a step of applying ferric chloride to the polyethylene oxide-based block copolymer, and a step of reducing.COPYRIGHT KIPO 2013본 발명은 pH 및 글루코스에 응답성이 있고 약물 전달용 고분자 소재로 사용될 수 있는 보론산기를 가지는 폴리에틸렌옥사이드계 블록공중합체, 그의 제조방법, 및 암 조영 (tumer cell imaging) 및 열치료 (hyperthermia)에 사용될 수 있는 상기 폴리에틸렌옥사이드계 블록공중합체에 의해 안정화된 산화철 나노입자에 관한 것이다.
